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Box plots of trough nelfinavir (A), M8 (B and D) and the sum of nelfinavir + M8 (C) concentrations simulated from the population model for 1250 mg nelfinavir twice daily according to comedication with zidovudine (A, B and C) or age quartiles (D) (the boxes represent 25th to 75th percentiles, with the median shown within the boxes; capped bars represent 1.5 times the interquartile range)
