. 2005 May;59(5):524–535. doi: 10.1111/j.1365-2125.2005.02368.x

Table 2.

Analysis of morphine and oxycodone area under the plasma concentration–time curve to 120 min (median AUC₁₂₀) in relation to dose composition

Treatment	Mor (ng min ml⁻¹)	M3G (ng min ml⁻¹)	M6G (ng min ml⁻¹)	Oxy (ng min ml⁻¹)	Noxy (ng min ml⁻¹)
M15	5653	21977	4558	0	0
M10/O5	3500	16349	3063	2031	228
M7.5/O7.5	2659	13080	2143	3014	408
M5/O10	1885	7819	1690	3988	476
O15	0	0	0	6838	714

	Dose-normalized median AUC₁₂₀ values
ng min ml⁻¹ per mg morphine)	ng min ml⁻¹ per mg morphine)	ng min ml⁻¹ per mg morphine)	ng min ml⁻¹ per mg oxycodone)	ng min ml⁻¹ per mg oxycodone)
M15	377	1465	304	0	0
M10/O5	350	1635	306	456	48
M7.5/O7.5	355	1744	286	399	48
M5/O10	377	1564	338	402	54
O15	0	0	0	406	46

M15, Morphine 15 mg; M10/O5, morphine mg +oxycodone 5 mg; M7.5/O7.5, morphine 7.5 mg +oxycodone 7.5 mg; M5/O10, morphine 5 mg +oxycodone 10 mg; O15, oxycodone 15 mg; Mor, morphine; M3G, morphine 3-glucuronide; M6G, morphine 6-glucuronide; Oxy, oxycodone; Noxy, noroxycodone.