Skip to main content
. 2005 Jun;59(6):705–711. doi: 10.1111/j.1365-2125.2005.02239.x

Table 2.

Values for constant a, exponent b and r2 for the pharmacokinetic parameters of propofol, based on data from rats [11], children [14] and adults [12] using the allometric equation Y = a × BWb (see Figure 1)

Parameter Constant a Exponent b r2
CL 0.071 0.78 0.9898
Q 0.062 0.73 0.9832
V1 0.30 0.98 0.9774
V2 1.2 1.1 0.9944

CL = clearance, Q = intercompartmental clearance, V1 = volume of central compartment and V2 = volume of peripheral compartment.