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. 2006 Jan;61(1):39–48. doi: 10.1111/j.1365-2125.2005.02530.x

Table 5.

Concentrations during the two study periods and for the simulation study. Target concentration intervention (TCI) resulted in improved concentration profiles

Concentration 1999–2002 n = 129 2002–2004 n = 76 Total study period n = 205 Predictive check n = 1000 TCI n = 1000
<5 mg l1 27.9% 61.8% 40.5% 36% 87%
>20 mg l1 94.5% 93% 94.2% 94% 77%
Average concentration1 18.8 mg l1 12.9 mg l1 16.5 mg l1 16.6 mg l1 8.8 mg l1
1

Estimated from geometric mean of measured (or simulated) peak and trough concentrations.