Table 2.
Mean ± s.e.mean per treatment | Treatment effect | |||||||
---|---|---|---|---|---|---|---|---|
CET | PLA | MEQ | DEX | F | d.f. | P | N | |
Day 1 | ||||||||
Subjective driving quality | ||||||||
Pre-test (mm) | 78.5 ± 4.6 | 73.7 ± 6.3 | 79.1 ± 6.5 | 68.7 ± 6.3 | 1.06 | 3,39 | NS | 15 |
Post-test (mm) | 64.7 ± 6.9 | 67.9 ± 6.6 | 55.1 ± 7.5b | 51.5 ± 8.0a | 4.55 | 3,39 | 0.008 | 15 |
Sleep questionnaire | ||||||||
Time before asleep (min) | 18.9 ± 4.6 | 12.4 ± 2.2 | 18.8 ± 4.5 | 22.6 ± 5.0 | 1.06 | 3,39 | NS | 15 |
Number of awakenings | 1.1 ± 0.3 | 1.1 ± 0.3 | 1.0 ± 0.3 | 1.1 ± 0.4 | 0.00 | 3,39 | NS | 15 |
Sleep (h) | 6.7 ± 0.3 | 7.6 ± 0.2 | 7.2 ± 0.2 | 7.1 ± 0.3 | 2.05 | 3,39 | NS | 15 |
Number of complaints | 2.6 ± 0.9 | 1.0 ± 0.4 | 1.7 ± 0.9 | 2.7 ± 0.9 | 1.23 | 3,39 | NS | 15 |
Day 8 | ||||||||
Subjective driving quality | ||||||||
Pre-test (mm) | 86.7 ± 3.0 | 77.5 ± 5.8 | 73.0 ± 4.2 | 72.2 ± 6.4 | 2.66 | 3,39 | NS | 15 |
Post-test (mm) | 62.7 ± 7.8 | 64.3 ± 5.7 | 59.5 ± 6.5 | 62.3 ± 6.5 | 0.23 | 3,39 | NS | 15 |
Sleep questionnaire | ||||||||
Time before asleep (min) | 22.9 ± 7.1 | 22.3 ± 6.8 | 14.6 ± 3.1 | 14.4 ± 2.1 | 1.14 | 3,39 | NS | 15 |
Number of awakenings | 0.8 ± 0.3 | 0.7 ± 0.3 | 0.7 ± 0.2 | 1.3 ± 0.4 | 1.46 | 3,39 | NS | 15 |
Sleep (h) | 7.2 ± 0.2 | 7.4 ± 0.2 | 7.5 ± 0.2 | 7.3 ± 0.3 | 0.36 | 3,39 | NS | 15 |
Number of complaints | 1.9 ± 0.7 | 2.6 ± 1.0 | 1.5 ± 0.4 | 1.8 ± 0.6 | 0.60 | 3,39 | NS | 15 |
Abbreviations are as indicated in Table 1 Significant drug–placebo differences are indicated by.
P < 0.017;
P < 0.025. High scores on the subjective driving quality indicate better driving performance.