Table 3.
Mean [min–max] observed retinal blood flow (arbitrary units, AU), measured as mean flow, systole, diastole and pulsation after administration of placebo or pentoxifylline (Ptx) 300 mg intravenous infusion alone or in combination with a ciprofloxacin (PtxC) 750-mg tablet or pretreatment with rifampicin (PtxR) 600-mg tablets once daily for 7 days
| Mean flow AU | Systole AU | Diastole AU | Pulsation | ||
|---|---|---|---|---|---|
| Observations | Placebo | 252 | 339 | 169 | 0.50 |
| [140–472] | [173–614] | [73–395] | [0.23–0.72] | ||
| Ptx | 260 | 343 | 183 | 0.46 | |
| [158–504] | [197–651] | [80–431] | [0.21–0.74] | ||
| PtxC | 248 | 328 | 172 | 0.47 | |
| [118–467] | [204–597] | [73–387] | [0.17–0.71] | ||
| PtxR | 265 | 344 | 188 | 0.45 | |
| [170–452] | [221–606] | [81–358] | [0.16–0.70] | ||
| Geometric least-square estimates | Placebo | 238 | 322 | 157 | 0.50 |
| (199, 284) | (272, 380) | (129, 191) | (0.45, 0.55) | ||
| Ptx | 249 | 331 | 172 | 0.46 | |
| (208, 298) | (280, 390) | (142, 209) | (0.42, 0.50) | ||
| PtxC | 239 | 318 | 165 | 0.46 | |
| (200, 285) | (270, 376) | (136, 200) | (0.42, 0.51) | ||
| PtxR | 250 | 327 | 176 | 0.47 | |
| (209, 299) | (277, 386) | (145, 213) | (0.41, 0.49) | ||
| Arithmetic least-square estimates | Placebo | 245 | 331 | 164 | 0.50 |
| (194, 297) | (271, 391) | (123, 205) | (0.46, 0.55) | ||
| Ptx | 259 | 342 | 181 | 0.47 | |
| (207, 310) | (282, 401) | (140, 222) | (0.439, 0.51) | ||
| PtxC | 247 | 328 | 172 | 0.47 | |
| (195, 298) | (268, 388) | (131, 213) | (0.43, 0.51) | ||
| PtxR | 256 | 332 | 182 | 0.45 | |
| (204, 307) | (273, 392) | (141, 223) | (0.41, 0.50) |
Geometric and arithmetic least-square estimates of means (95% confidence intervals) of retinal blood flow, measured as mean flow, systole, diastole and pulsation after administration of placebo or pentoxifylline 300 mg intravenous infusion alone or in combination with a ciprofloxacin 750-mg tablet or pretreatment with rifampicin 600-mg tablets once daily for 7 days.