Table 4.

Relative differences between least-square estimates of means (95% confidence intervals) of retinal blood flow, measured as mean flow, systole, diastole and pulsation after administration of placebo or pentoxifylline (Ptx) 300-mg intravenous infusion alone or in combination with a ciprofloxacin (PtxC) 750-mg tablet or pretreatment with rifampicin (PtxR) 600-mg tablets once daily for 7 days

	Mean flow %	Systole %	Diastole %	Pulsation %
Ptx–placebo	4.6*	2.7	9.7*	−7.8*
	(1.1, 8.3)	(−1.0, 6.7)	(4.2, 15.5)	(−12.3, 3.1)
PtxC–placebo	0.4	−1.1	5.0	−6.6*
	(−3.0, 3.9)	(−4.6, 2.7)	(−0.2, 10.6)	(−11.2, 1.8)
PtxR–placebo	5.1*	1.5	11.7*	−10.2*
	(1.4, 7.8)	(−2.4, 5.6)	(5.8, 17.9)	(−14.8, 5.4)
PtxC–Ptx	−4.1*	−3.6	−4.2	1.2
	(−7.1, −0.9)	(−7.0, 0.01)	(−8.8, 0.6)	(−3.5, 6.3)
PtxR–Ptx	0.5	−1.2	1.8	−2.6
	(−2.9, 3.9)	(−4.8, 2.6)	(−3.3, 7.2)	(−7.4, 2.4)
PtxR–PtxC	4.7*	2.6	6.3*	−3.8
	(1.2, 8.4)	(−1.2, 6.5)	(0.9, 11.9)	(−8.5, 1.1)

^*P < 0.05.