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Observed (○) and population predicted concentrations (•) of chlorcycloguanil (CCG) vs. time for healthy volunteers, and Zambian adults and Gambian children with Plasmodium falciparum malaria. [Note there are different population predicted concentrations at the same time points due to the different exact dosages received and due to the differences in the posterior individual estimates of ka, CL/F and V1/F from modelling of the chlorproguanil (CPG) data.]
