Table 2b.
Drugs/age | Pred CL (0.75) | Pred CL (0.80) | Pred CL (0.85) | Pred CL (1.0) | Pred CL L + K | Pred CL (mixed) |
---|---|---|---|---|---|---|
Caffeine | ||||||
1–7 days (premature) | −3046 | −2531 | −2100 | −1192 | −1523 | −1192 |
7–28 days (premature) | −1439 | −1214 | −1022 | −600 | −728 | −600 |
1–3 months | −225 | −185 | −150 | −68 | −84 | −68 |
3–12 months | −41 | −26 | −13 | 18 | 4 | 18 |
Vancomycin | ||||||
7–28 days (premature) | −164 | −125 | −92 | −20 | −42 | −20 |
1–7 days (term) | −251 | −200 | −156 | −60 | −89 | −60 |
7–28 days (term) | −184 | −146 | −113 | −39 | −57 | −39 |
1–3 months | −29 | −13 | 1 | 34 | 27 | 34 |
3–12 months | −37 | −23 | −11 | 20 | 6 | 20 |
Cefetamet | ||||||
I.v. 3–5 years | 9 | 16 | 22 | 37 | 24 | 24 |
5.5–12 years | 3 | 7 | 10 | 21 | 12 | 3 |
Chloramphenicol | ||||||
Premature | −400 | −318 | −250 | −105 | −158 | −105 |
Infant | −174 | −141 | −111 | −42 | −56 | −56 |
Child | −211 | −192 | −174 | −127 | −167 | −167 |
Valproic acid | ||||||
0–2 months | −94 | −69 | −49 | 0 | −10 | 0 |
2–36 months | −24 | −12 | −2 | 24 | 15 | −24 |
3–9 years | −37 | −29 | −22 | −2 | −19 | −37 |
10–18 years | 16 | 17 | 18 | 22 | 20 | 16 |
Erythromycin estolate | ||||||
1.5 days | −62 | −39 | −19 | 26 | 13 | 26 |
15 days | −90 | −64 | −41 | 10 | −4 | 10 |
0.29 days | −72 | −49 | −29 | 16 | 5 | 16 |
19 months | −211 | −184 | −159 | −96 | −153 | −153 |
Tiagabine | ||||||
Valproate 6 years | 39 | 42 | 45 | 54 | 47 | 39 |
Induced 6 years | −7 | −1 | 4 | 18 | 6 | −7 |
Omeprazole | ||||||
0.25–1 year | −99 | −77 | −58 | −12 | −34 | −12 |
0.3–1.6 years | −111 | −91 | −74 | −30 | −47 | −47 |
4–15 years | −116 | −107 | −99 | −75 | −94 | −116 |