Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Plasma imatinib concentrations observed in patients receiving imatinib, together with the mean population prediction (solid line) and 90% prediction interval (dashed lines). The graphs represent a once (upper part) or twice (lower part) daily regimen, based either on the demographic covariates model (left) or on the final α1-acid glycoprotein (AGP) model (right) (values adjusted to 400 mg q.d.; AGP model curves generated assuming mean values of AGP level and fu)
