Figure 3.

The percentage of predicted C_ss falling out of therapeutic range at different infusion rates (8.3, 5.8, 5.0, 4.2 IU kg⁻¹ h⁻¹) for intensive care unit patients with different renal function (1, CrCL <30 ml min⁻¹; 2, CrCL 30–50 ml min⁻¹; 3, CrCL >50 ml min⁻¹). Dashed lines represent the 5th and 95th percentiles (90% PI). (a) Percentage of predicted C_ss which is <0.5 IU ml⁻¹. ♦, 4.2 IU/kg/h; ▪, 5.0 IU/kg/h; ▪, 5.8 IU/kg/h; •, 8.3 IU/kh/h. (b) Percentage of predicted C_ss which is >1.2 IU ml⁻¹. ♦, 4.2 IU kg⁻¹ h⁻¹; ▪, 5.0 IU kg⁻¹ h⁻¹; ▴, 5.8 IU kg⁻¹ h⁻¹; •, 8.3 IU kg⁻¹ h⁻¹. (c) Percentage of predicted C_ss falling out of therapeutic range (0.5–1.2 IU ml⁻¹) when patients with CrCL <30 ml min⁻¹ received enoxaparin at 4.2 IU kg⁻¹ h⁻¹ infusion rate, with CrCL between 30 and 50 ml min⁻¹ received enoxaparin at 5.0 IU kg⁻¹ h⁻¹ infusion rate and with CrCL >50 ml min⁻¹ received enoxaparin at 5.8 IU kg⁻¹ h⁻¹ infusion rate. ▪, >1.2 IU ml⁻¹; •, <0.5 IU ml⁻¹