Figure 2.

Relationship between the dose of SJW and D/C ratio of CsA at the steady state. Dose-to-trough blood concentration ratio (D/C ratio) of CsA in the SJW period and SJW-free period at the steady state was calculated in nine cases and plotted. The latest blood sampling time during the SJW period was employed to calculate the D/C ratio for the SJW period. The mean D/C ratio of the SJW-free (control) period for each case (case 1–4, 6–9) was assigned as the D/C (control) except for case 5, in which the latest D/C ratio during the SJW free period was employed as D/C (control). The line represents the parameter obtained by this analysis and points represent the ratio of D/C (SJW) to D/C (control) calculated in each case