Figure 2.

Genomic location of SLC22A6, SLC22A8 and SLC22A11 on chromosome 11 as given by the ‘Map Viewer’ of the NCBI showing that there are several other genes between the SLC22A6-SLC22A8 locus and the SLC22A11 locus. The arrows denote the transcription direction. The intron–exon structure of the genes is given according to the ‘Gene’ database of the NCBI; the grey boxes denote exons and the narrow boxes untranslated regions. The polymorphisms studied are identified by their rs-number and their position on chromosome 11 according to the ‘SNP’ database of the NCBI March 2005. Two putative polymorphisms, identified when comparing genomic databases had no reference number (OAT3_goe 1 and 2). The three putative polymorphisms that turned out to be monomorphic are given in grey letters