Table 1.
Unadjusted and multivariate estimates of acute coronary syndrome risk
| Patient characteristics | Cases, n = 328 n (%) | Controls, n = 478 n (%) | Crude OR | 95% CI (OR) | Adjusted OR | 95% CI (OR) |
|---|---|---|---|---|---|---|
| Age (years)* | 67.04 (56.55–76.75) | 64.16 (52.81–75.13) | 1.01 | (1.00, 1.02) | 1.01 | (0.99, 1.02) |
| Male | 209 (63.7) | 282 (59.0) | 1.22 | (0.91, 1.63) | 1.29 | (0.93, 1.78) |
| Risk factors | ||||||
| Hypertension | 189 (58.6) | 176 (36.8) | 2.33 | (1.75, 3.11) | 1.84 | (1.31, 2.56) |
| High cholesterol | 169 (51.5) | 107 (22.4) | 3.68 | (2.72, 5.00) | 2.94 | (2.11, 4.08) |
| Smoking | ||||||
| Never | 107 (32.6) | 191 (40.0) | ||||
| Past | 122 (37.2) | 169 (35.4) | ||||
| Current | 99 (30.2) | 118 (24.7) | 1.32 | (0.96, 1.81) | 2.08 | (1.42, 3.05) |
| Of those who could recall dose | ||||||
| NSAID use in the week before being in hospital | ||||||
| None (reference) | 256 (78.0) | 352 (73.6) | 1.00 | |||
| Celecoxib | 23 (7.0) | 27 (5.6) | 1.17 | (0.66, 2.09) | 1.11 | (0.59, 2.11) |
| Rofecoxib | 15 (4.6) | 28 (5.9) | 0.74 | (0.39, 1.41) | 0.63 | (0.31, 1.28) |
| Other NSAIDs | 34 (10.4) | 71 (14.9) | 0.66 | (0.42, 1.02) | 0.67 | (0.41, 1.09) |
| Aspirin | 151 (46.9) | 124 (2.9) | 2.43 | (1.81, 3.28) | 1.77 | (1.27, 2.47) |
| Antiplatelet drug | 39 (11.9) | 13 (2.7) | 4.83 | (2.53, 9.20) | 3.42 | (1.73, 6.79) |
*
Median (Q1–Q2). OR, Odds ratio; CI, confidence interval. Adjustment was made for age, gender, hypertension, elevated cholesterol, current smoking status, aspirin use and antiplatelet drug use in the logistic regression model.