Table 4.
Summary of blood pressure (mmHg) results for the whole group (A + B + C)
n = 112 | Screening | Tadalafil | Screening-tadalafil | Placebo | Screening-placebo | P-value |
---|---|---|---|---|---|---|
SBP | 137 | 129 | −7.9 | 134 | −3.1 | <0.01 |
(135, 140) | (127, 131) | (6.7, 9.1) | (132, 137) | (1.8, 4.3) | – | |
DBP | 84 | 78 | −5.4 | 82 | −2.3 | <0.01 |
(82, 85) | (77, 80) | (4.6, 6.2) | (80, 83) | (1.3, 3.2) | – | |
HR | 68 | 69 | 1 | 67 | −1 | NS |
Data are mean (95% CI); SBP, systolic blood pressure; DBP diastolic blood pressure; HR, heart rate; data analysed using anova (SPSS v 11.5) with change from screening in mean 26-h ambulatory blood pressure monitor BP as the dependant variable, screening mean SBP as a covariate and antihypertensive treatment as a between-subject factor.