Table 2.

Control of INR and incidence of complications

	Pharmacist-managed group	Physician-managed group	P-value
Patient time (%) in therapeutic INR range	64	59	< 0.001
Patient time (%) in therapeutic range for the group with target INR of 2–3	64	60	< 0.001
Patient time (%) in therapeutic range for the group with target INR of 2.5–3.5	66	44	< 0.001
Patient time (%) in expanded therapeutic range*	78	76	< 0.001
Numbers with bleeding (number per 100 patient-years)
Major	1 (1.6)	2 (3.1)	1.00
Fatal	0	0
Number of thromboembolic events (number per 100 patient-years)
Major	1 (1.6)	1 (1.6)	1.00
Fatal	0	0

^*Expended therapeutic range = therapeutic range±0.2 international normalized ratio (INR) units.