Table 2.

Distribution of the plasma concentrations of non-nucleoside reverse transcriptase inhibitors and protease inhibitors

Antiretroviral drug	Number	Concentration (mg l−1)*	CV (%)	Optimal n (%)
Nevirapine	18	5.31 (2.13)	40.1	5 (27.8)
Efavirenz	442	3.62 (1.70)	46.9	26 (61.9)
Lopinavir	43	7.26 (3.91)	53.8	35 (81.4)
Nelfinavir	7	3.02 (1.11)	36.7	7 (100)
Saquinavir/rtv	1	0.350		1 (100)
Amprenavir/rtv	2	2.06 (1.66–2.45)†		2 (100)
Atazanavir	3	0.67 (0.62–1.52)†		3 (100)
Indinavir	1	0.10		1 (100)
Total	117			80 (68.4)

CV, Coefficient of variation; rtv, ritonavir.

^*Data are expressed as mean (SD), except where noted.

^†Median (interquartile range).