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. 2007 Jun 13;2(6):e517. doi: 10.1371/journal.pone.0000517

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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Panel A. Effects of the K27E rpl5 mutanton misreading of seven missense codons. Effects on the indicated missense reporters are depicted as fold of isogenic wild-type cells. ** indicates p values of <0.01. Panel B. Paromomycin dilution spot assays. Ten-fold dilutions (10⁶→10¹ CFU) of logarithmically growing cells were arrayed onto H-leu medium containing paromomycin (1 mg/ml) or no drug control plates. Cells were grown at 25°C for 3 days.