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. Author manuscript; available in PMC: 2008 Mar 1.
Published in final edited form as: Nanomedicine. 2007 Mar;3(1):32–42. doi: 10.1016/j.nano.2006.11.005

Figure 5.

Figure 5

Agarose gel eletrophoresis to show stability of EGFP-N1 plasmid DNA encapsulated in gelatin (Gel), thiolated gelatin (SH-Gel), poly(ethylene glycol)-modified gelatin (PEG-Gel), and poly(ethylene glycol)-modified thiolated gelatin (PEG-SHGel) nanoparticles. The nanoparticles were treated with 0.2 mg/ml of protease or 0.2 units (per batch of nanoparticles) of DNAse-I. The sequence of enzyme addition was either protease followed by DNAse to degrade the matrix and release the plasmid or DNAse followed by protease to show that the plasmid was physically encapsulated in the matrix and did not undergo degradation.