Table 2.

Distribution of LOC387715-G/T among Cases and Controls from the AREDS and NEI Protocols

			Geograpihic Atrophy		Choroidal Neovascularization		Combined
Genotypes	Control	Case	P	OR (95%CI) vs. GG	P	OR (95%CI) vs. GG	P	OR (95%CI) vs. GG
GG	217 (66.0%)	148 (37.1%)	Reference	1	Reference	1	Reference	1
GT	100 (30.4%)	182 (45.6%)	3.40 × 10−7	2.87 (1.91–4.30)	2.29 × 10−6	2.48(1.70–3.61)	1.42 × 10−9	2.61 (1.89–3.61)
TT	12 (3.65%)	69 (17.3%)	1.73 × 10−6	6.43 (3.00–13.79)	2.39 × 10−11	10.12(5.12–20.01)	3.56 × 10−13	8.59 (4.49–16.46)
GT+TT	112(34.0%)	251 (69.2%)	2.07 × 10−8	3.24 (2.20–4.78)	2.92 × 10−10	3.0 (2.32–4.70)	9.06 × 10−15	3.25 (2.39–4.41)
G	534 (81.2%)	478 (59.9%)	Reference	1	Reference	1	Reference	1
T	124 (18.8%)	320 (40.1%)	3.97 × 10−11	2.64 (1.97–3.54)	5.46 × 10−17	3.10(2.37–4.06)	1.80 × 10−18	2.88 (2.26–3.67)