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. 2007 Jun 1;3(6):e87. doi: 10.1371/journal.pgen.0030087

Figure 8. Most of the Sequences Flanking the 1,234 ER Binding Sites Are Not Conserved through Evolution.

Figure 8

Measure of species conservation at all 1,234 ER binding sites from the center of the ChIP-PET cluster is depicted in the blue line. The green line measures species conservation of randomly selected fragments. The red line depicts the degree of conservation in 22% (273/1,234) of the binding sites bearing conserved elements, and the yellow line shows the degree of species conservation of the remaining 78% (961/1,234) of the binding sites that harbor no conserved elements. These results show that most of the conservation signal is driven by a minority of the binding sites. Conservation was measured by base-by-base comparisons.