Figure 10. Nonrandom Positional Distribution of AP-1, SF1, MAF, PAX3, PAX2, CDX, and AML1 (as Negative Control) Binding Sites in the 500-bp Window Centered on the Main ERE.

The y-axis represents the cumulative frequency of the specific transcription factor motif, and the x-axis represents the position of that motif relative to the ERE centered at position 250. Motif hits are marked in red “+” and green “X” indicating forward and reverse strand hits respectively. Multiple hits on the same sequence are depicted as multiple marks on the same y-value sequence.