Villanueva Goldner stain of undecalcified sections. Ectopic bone formation (arrow heads) was seen in the pores of C-u-HA70. (a) and (b) Three months after implantation of C-u-HA70; (c) and (d) Twelve months after implantation of C-u-HA70. (a) and (c) Original magnification ×20; scale bar, 1 mm. (b) and (d) Original magnification ×100; scale bar, 200 μm. BM, bone-marrow tissue; M, material; NB, newly formed bone.