ACAP2 |
+ |
GTPase-activating protein, activates ARF6, a regulator of cell adhesion and motility |
CapZ2 |
+ |
F-actin capping protein |
Bid |
+ |
Pro-apoptotic Bcl-2 family protein |
Nip1 |
+ |
Nuclear cap binding protein |
Phospho-p38 |
+ |
Active form of p38 MAP kinase, mediates stress related transcription/cell cycle control |
MEK2 |
+ |
Dual specificity protein kinase, activates MAPK1/ERK2 and MAPK2/ERK3 |
Sema4c |
+ |
Semaphorin, linked to differentiation and development |
Caspase 7 |
− |
Apoptotic caspase, activated by caspase 3 or caspase 10 |
Caspase 14 |
− |
Apoptotic caspase, activated by caspase 8 or caspase 10 |
Rip2 |
− |
Receptor interacting protein, has apoptosis inducing activity |
Cdk2 |
− |
Cyclin dependent kinase, essential for G1/S transition |
RAS-GAP |
− |
GTPase activating protein, down regulates ras signaling |
Rho-GDI |
− |
GDP dissociation inhibitor, stimulates signaling through Rho, a GTPase that regulates focal adhesions and stress fibers |
ROCK-D1 |
− |
Serine/threonine kinase, activated by Rho, a GTPase that regulates focal adhesions and stress fibers |