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. 2000 Oct 24;97(23):12858–12863. doi: 10.1073/pnas.220256497

Figure 1.

Figure 1

Synaptosomes exhibit high-affinity Glu uptake. Glu uptake was measured in synaptosomal preparations (P3; see Fig. 3A) derived from pleural-pedal ganglia. Synaptosomal Glu uptake was measured from control (solid line, ●) and experimental (500 μM 5-HT, dashed line, ◊) animals 24 h after treatment. Glu uptake by synaptosomes was dose dependent. Note the apparent increase in Vmax from synaptosomes isolated 24 h after treatment of animals with 5-HT. (Inset) Lineweaver–Burk analysis of data in main graph. Each experiment contained synaptosomes derived from 8–10 pleural-pedal ganglia. In this and subsequent illustrations, error bars are SEM.