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. 2000 Oct 24;97(23):12858–12863. doi: 10.1073/pnas.220256497

Figure 5.

Figure 5

Emetine and DRB block long-term sensitization and the long-term increase in Glu uptake. Electrical stimulation applied to one side of an animal induced long-term sensitization of the siphon withdrawal reflex 24 h after stimulation (F = 12.98, df = 13, P < 0.0005). Injection of emetine (n = 3) or DRB (n = 3) into Aplysia 30 min before electrical stimulation significantly inhibited the appearance of long-term sensitization (P < 0.05). The long-term increase in Glu uptake produced by electrical stimulation (n = 5) was significantly inhibited by injection of emetine (n = 4, P < 0.05) or DRB (n = 3, P < 0.05).