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. Author manuscript; available in PMC: 2007 Jun 1.
Published in final edited form as: Vaccine. 2007 Jan 10;25(17):3437–3444. doi: 10.1016/j.vaccine.2006.12.045

Figure 5.

Figure 5

Mean Tumor Volume in Therapeutic E7IR Vaccine Treatment. In therapeutic experiments with the E7IR vaccine, 2×104 TC-1 cells per mouse were injected into 5 mice per group on day 0. After all mice in all groups had a palpable tumor (day 10), the first gene gun vaccination was given, followed by a second vaccination 7 days later. Numbers equal the number of tumor bearing mice in each group at day 34, the last day that all mice were living. Data is representative of two experiments. A composite p value generated from these two experiments indicates that vaccination with the E7IR construct showed a significant decrease in tumor volume compared to vaccination with the E7WT construct (p = 0.01).