Fig. 2.
The thrifty phenotype hypothesis (Hales & Barker, 2001; Gluckman & Hanson, 2004). Exposure of the developing organism to a low plane of nutrition promotes metabolic thrift in order to ensure survival. In a postnatal environment in which nutrients are in short supply this metabolic thrift continues to be a survival trait, but if nutrients are present in excess the thrifty trait will promote the metabolic syndrome.