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Comparative biodistributions using all 3 conjugates in combination or with each conjugate singly at 48 hours. Combination studies in Ramos (A), Raji (B), and FL-18 (C) as described for Figure 4. Each graph shows results 48 hours after injecting 111In-DOTA-biotin pretargeted with either 1.4 nmol 1F5/SA alone (□), Lym-1/SA alone (▩), HD39 alone (■), and all 3 used in combination at 0.47 nmol/conjugate (▤) and at 1.4 nmol/conjugate (▧).
