Fig. 1.

Pathways of methanogenesis and CO₂ assimilation in M. maripaludis. Enzymes are listed next to each reaction. Bar graphs show the log₂ expression ratios for the gene(s) coding for each enzyme. For enzymes with multiple genes, the bar graph shows the average log₂ expression ratio. Numbers below bars indicate corresponding nonlogged ratios. Fmd, formylmethanofuran dehydrogenase (molybdenum-containing); Ftr, formylmethanofuran:tetrahydromethanopterin formyltransferase; Mch, methenyltetrahydromethanopterin cyclohydrolase; Mer, methylenetetrahydromethanopterin reductase; Mtr, methyltetrahydromethanopterin:coenzyme M methyltransferase; Cdh, carbon monoxide dehydrogenase/acetyl CoA synthase. Log₂ ratios for leucine limitation vs. phosphate limitation are from unpublished work.