Table 1.

Recombination phenotypes of strains with varying amounts of MutS and MutL proteins

Genotype	Recombination frequency
	Mean ± SEM	Fold difference	n
100% identical lacZ repeats
Wild-type	6.8 × 10−4 ± 6.0 × 10−5	1.00	6
recA	7.9 × 10−5 ± 1.2 × 10−5	0.11*	3
mutS	6.1 × 10−4 ± 5.5 × 10−5	0.89	3
mutL	6.5 × 10−4 ± 1.0 × 10−4	0.94	3
mutLdown + tc	6.7 × 10−4 ± 6.2 × 10−5	0.98	3
Wild-type pVector	1.8 × 10−3 ± 6.3 × 10−4	1.00	3
Wild-type pMutL	1.4 × 10−3 ± 2.8 × 10−4	0.79	3
Wild-type pMutS	2.2 × 10−3 ± 4.7 × 10−4	1.20	3
4% diverged lacZ repeats
Wild-type	2.5 × 10−6 ± 2.0 × 10−7	1.00	6
recA	1.2 × 10−7 ± 1.0 × 10−8	0.05*	4
recF	2.1 × 10−6 ± 6.4 × 10−7	0.83	3
recB	1.1 × 10−6 ± 1.1 × 10−7	0.45*	5
recF recB	1.3 × 10−7 ± 1.6 × 10−8	0.05*	6
lexA1	2.3 × 10−6 ± 3.3 × 10−7	0.93	5
mutS	6.4 × 10−4 ± 7.9 × 10−5	251.14*	4
mutL	5.1 × 10−4 ± 6.8 × 10−5	199.49*	3
mutH	9.9 × 10−5 ± 2.9 × 10−5	38.90*	3
uvrD	2.0 × 10−4 ± 7.5 × 10−5	81.30*	4
dam	1.7 × 10−4 ± 1.2 × 10−5	65.99*	5
mutLdown+ tc	1.1 × 10−5 ± 2.6 × 10−6	4.99*	6
mutLdown − tc	3.1 × 10−4 ± 2.6 × 10−5	121.41*	3
Wild-type pVector	5.2 × 10−6 ± 4.6 × 10−7	1.00	4
Wild-type pMutL	2.2 × 10−6 ± 3.5 × 10−7	0.42*	6
Wild-type pMutS	8.1 × 10−6 ± 3.7 × 10−6	1.55	5
recA	1.2 × 10−7 ± 1.0 × 10−8	1.00	4
recA mutS	5.6 × 10−5 ± 5.7 × 10−6	440.37*	3
recA mutL	7.0 × 10−5 ± 4.8 × 10−5	548.53*	3
recA mutH	3.2 × 10−5 ± 1.7 × 10−5	254.27*	3
recA mutLdown + tc	8.6 × 10−7 ± 9.9 × 10−8	6.80*	3
recA pVector	5.8 × 10−7 ± 1.9 × 10−7	1.00	6
recApMutL	2.9 × 10−7 ± 5.7 × 10−8	0.49	6
recApMutS	5.9 × 10−7 ± 2.1 × 10−7	1.02	6

Genetic requirements for deletion formation between identical and diverged repeats are shown. Fold difference is the ratio of the value for a given strain to the value of the control strain, i.e., the first strain in every subdivision of the column. tc, tetracycline.

*Difference is significant according to Mann–Whitney test, P < 0.05.