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Percentage of different mutation types in rpoB
| Genotype | Transitions |
Transversions |
||||
|---|---|---|---|---|---|---|
| AT→GC | GC→AT | AT→TA | AT→CG | GC→TA | GC→CG | |
| Wild type | 28 | 49 | 15 | 4 | 2 | 2 |
| mutLdown + tc | 27 | 43 | 20 | 2 | 9 | 0 |
| mutL | 88 | 11 | 0 | 0 | 0 | 0 |
Fifty-three, 56, and 44 rpoB genes of wild-type, mutLdown + tc, and mutL rifampicinR mutants were analysed by sequencing, respectively; For sequencing protocol see SI Text. tc, tetracycline.
