Figure 7.

Kidney glomerulonephritis and immunoglobulin deposition in ABCA1−/− mice. A: H&E-stained kidney sections from healthy ABCA1+/+ (left), inflammatory cell-infiltrated ABCA1−/− (middle), and diseased 55.2 ABCA1−/− (right) mice. Original magnification, ×250. Scarring of glomeruli was visible when sections were stained with trichrome (data not shown). G, glomerulus. B: Heavy deposition of immunoglobulin was found in glomeruli of 64.7 ABCA1−/− animal (right) but was not present in ABCA1+/+ glomeruli (left). Original magnification, ×100.