Apoptosis in mIMCD-3 cells transfected with anti-sense PAX2 cDNA. Cells transfected with caspase-2 (A), anti-sense PAX2 (B), and sense PAX2 (C) vectors and β-Gal marker. Cells transfected with caspase-2 (D), anti-sense-PAX2 (E), and sense-PAX2 (F) and GFP marker. Apoptotic condensed cells (arrows) at early stage of apoptosis (A, B, and E) and vesicular apoptotic bodies (arrow, D) at late apoptosis stages are indicated.