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Anti-sense PAX2 causes increased apoptosis of cells expressing a high endogenous level of PAX2 protein. mIMCD-3 (A), COS-7 (B), and HEK293 (C) cells transfected with β-Gal marker alone, anti-sense-PAX2 and sense-PAX2 expression vectors as described in Materials and Methods. *, P ≤ 0.0001. Each condition represents the average of 4 or 5 separate experiments; in some cases the SE bar is not visible.
