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Caspase inhibitor z-VAD-fmk rescues mIMCD-3 cells transfected with caspase-2 and anti-sense-Pax2 from apoptosis. A: Percentage of apoptosis in cells transfected with mutant or wild-type caspase-2 and treated with various concentrations of z-VAD-fmk. B: Percentage of apoptosis in cells transfected with sense-PAX2 or anti-sense-PAX2 and treated with various concentrations of z-VAD-fmk. *, P ≤ 0.0001. In some experiments, SE bars are not visible.
