Figure 1.
Proteinuria in experimental mice. Proteinuria was measured by gel electrophoresis of urine samples taken at weekly intervals from an individual set of experimental animals. The age of the mice (in weeks) at the time of sample collection is indicated above each lane. Group A(1) is the profile for an untreated 129 Sv/J Alport mouse; Group A(2) is that for a double-knockout mouse; Group B(1) is the extended profile for a double-knockout mouse; Group B(2) is a littermate double knockout treated with mTGFβR:Fc. Mr, molecular weight standards.