Table 1.
Expression of CD44v3 and c-Met in Colorectal Tumorigenesis
| Tissue | Expression level* | Number of patients n (%) | |
|---|---|---|---|
| CD44v3 | c-Met | ||
| Normal | |||
| Crypt base | Negative/low | 1 (17) | 3 (60) |
| Intermediate | 4 (67) | 2 (40) | |
| High | 1 (17) | 0 | |
| Upper crypt | Negative/low | 6 (100) | 3 (60) |
| Intermediate | 0 | 2 (40) | |
| High | 0 | 0 | |
| Polyp | Negative/low | 0 | 0 |
| Intermediate | 4 (67) | 2 (33) | |
| High | 2 (33) | 4 (67) | |
| Carcinoma | Negative/low | 16 (30) | 0 |
| Intermediate | 19 (35) | 0 | |
| High | 19 (35) | 54 (100) | |
*Negative/low, intermediate, high: expression on <10%, 10 to 50%; or >50% of the tumor cells, respectively.