Figure 1.

Semiquantitative analysis of IL-1β (a) and IL-1Ra (b) expression (number of positive cells) in liver grafts, assessed in the portal tracts and lobules. The numbers of positive cells for IL-1β and IL-1Ra were significantly higher during rejection than in patients without rejection, in both the lobule and portal tract (*, P < 0.03; **, P < 0.01; °, P < 0.05; °°, P < 0.02 versus patients without rejection). In contrast, there was no difference between patients with steroid-responsive and steroid-resistant acute rejection.