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. 2000 Nov;157(5):1587–1595. doi: 10.1016/S0002-9440(10)64796-7

Table 2.

Estimated Chromosome Copy Number Based on Combined Information of Number of Centromeric Signals Found Using FISH at Interphase Nuclei and Tumor Percentage (Shown in Italics)

Chromosome Probe Repetitive family Reference no. Case
114 408 178 262 215
tum%: 95% <50% 80% 75% 70%
1 pUC1.7 Satellite III 63 1 1* 2 and 4 2 2
3 pα3.5 Alphoid satellite 64 NS NS NS 2 2
6 p308 Alphoid satellite 65 1 1* 1 and 2 2 2
7 p7t1(αp7) Alphoid satellite 66 1 2 2 and 4 2 3*
8 D8Z2 (αp8) Alphoid satellite 67 1 1* 2 and 4 2 3*
9 pHUR98 (sp9) Satellite III 68 1 2 2 and 4 2 2
10 D10Z1 (αp10) Alphoid satellite 1 1* 1 and 2 2 2
11 pLC11A Alphoid satellite 69 1 1* 1 and 2 2 2
12 pα12H8 (αp12) Alphoid satellite 70 2 2 2 and 4 4 2
15 D15Z1 Satellite III 71 2 2 2 and 4 2 4*
16 pHUR195 Satellite II 68 1 1* 2 and 4 2 2
17 p17H8 Alphoid satellite 72 1 1* 2 and 4 2 3*
18 L1.84 (#18) Alphoid satellite 73 1 2 2 and 4 2 2
20 p3.4 Alphoid satellite 1 2 NS 4 NS
X pBAMX5 (αpX) Alphoid satellite 74 1 1 1 and 2 4 1*
Y DYZ3 Alphoid satellite 75 1 0 0 0 0

*Many nuclei show two copies of the chromosomes, because of a high percentage of nontumor nuclei. NS: nonsuccessful hybridization.