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. 2000 Dec;157(6):1955–1962. doi: 10.1016/s0002-9440(10)64834-1

Figure 3.

Figure 3.

A: Induction of MT1-MMP transcripts in gut mesenchymal cells after α4β1 integrin ligation. Gut mesenchymal cells were cultured with anti-VLA4 (10 μg/ml) or VCAM-IgG (10 μg/ml) for 2 days. TNF-α or ConA were used as positive controls. This experiment is one of two separate experiments in which identical results were obtained. B: Induction of MT1-MMP protein by VCAM-IgG or recombinant TNF-α. Mesenchymal cells were stimulated with VCAM-IgG, human-IgG (hu-IgG), or TNF-α for 2 days. Whole cell lysates were used for detecting MT1-MMP by Western blotting. This is a representative of two individual experiments with comparable results.