Table 1.

Somatic and Germline Mutations of the APC Gene in Multicentric Thyroid Carcinomas from FAP Patients

Patient	Thyroid carcinoma	Somatic mutation	Germline mutation
PLK29	TCa1	Codon 886 CAG → TAG	Codon 175 C deletion
PLK29	TCa2	Loss of normal allele	Codon 175 C deletion
PLK29	TCa3	Codon 1536 GAA → TAA	Codon 175 C deletion
PLK29	TCa4	Loss of normal allele	Codon 175 C deletion
PLK29	TCa5	Codon 1554–1556 A insertion	Codon 175 C deletion
PLK294	TCa1	Codon 857 GGA → TGA	Codon 1110 TCA → TGA
PLK294	TCa2	Codon 1060–1063 AAAAC deletion	Codon 1110 TCA → TGA