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. 2000 Dec;157(6):2065–2079. doi: 10.1016/S0002-9440(10)64845-6

Figure 3.

Figure 3.

Effect of calpain inhibitor I on myeloperoxidase activity and malondialdehyde levels in the lung. Myeloperoxidase (MPO) activity (A) and malondialdehyde (MDA) levels (B) in the lungs of carrageenan-treated rats killed at 4 hours. MPO activity and MDA levels were significantly increased in the lungs of the carrageenan-treated rats in comparison with sham rats (*P < 0.01). Calpain inhibitor I (5, 10, or 20 mg/kg) reduced the carrageenan-induced increase in MPO activity and MDA levels in a dose-dependent manner. Values are means ± SEM of 10 rats for each group. *P < 0.01 versus sham; °P < 0.01 versus carrageenan.