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. Author manuscript; available in PMC: 2007 Jun 4.
Published in final edited form as: Brain Res. 2006 Dec 26;1132(1):185–192. doi: 10.1016/j.brainres.2006.10.098

Fig. 2.

Fig. 2

Temporal profiles of the ischemic lesion size for the treated and control groups (a) and blood pressure measurements (b). Although the mean values of lesion size were lower in the treated group than in the control group (average from 1 to 6 weeks: 41% vs. 49% of the ipsilateral hemisphere), there was no significant difference between the two groups throughout the experimental period. Sildenafil administered subcutaneously to rats at a dose of 10mg/Kg resulted in a transient but not a significant reduction of blood pressure compared with the pre-treatment level, with the lowest mean blood pressure exhibited 40 minutes after administration and the value gradually returning to the pre-treatment level 120 minutes after administration.