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. 2006 Sep 8;362(1):78–88. doi: 10.1016/j.jmb.2006.06.079

Table 5.

Effects of interaction with pro domain residues

	Pro domain residues		Shift in C^α position (Å)
MMP-1 residues	van der Waals interactions	Hydrogen bonds	Shift in C^α position (Å)
Gly160	Pro71⁽²⁾, Arg72	Gly160 O–Arg72 N (2.9 Å)	0.87
Asn161	Arg72⁽²⁾, Gly74⁽⁴⁾	Asn161 ND2–Gly74 N (3.0 Å)	0.33
Leu162	Pro71⁽²⁾	Leu162 N–Arg72 O (2.9 Å)	0.33
Asn163	Cys73⁽²⁾, Gly74	Asn163 O–Gly74 N (2.8 Å)	0.09
His164	Val75	–	0.00
Ala165	Val75⁽²⁾	–	0.17
Tyr191	Pro71⁽⁶⁾	–	0.00
His199	Cys73⁽⁴⁾	–	0.36
His203	Cys73⁽²⁾, Val75⁽³⁾	–	0.50
His209	Phe51, Cys73⁽⁴⁾, Val75⁽⁴⁾, Pro76, Asp77	His209 ND1–Asp77 OD1 (2.7 Å)	0.44
Ser210	Phe51⁽⁴⁾	–	0.50
Thr211	Phe51⁽¹¹⁾	–	0.79
Tyr218	Phe52⁽⁴⁾	–	0.85
Pro219	Phe51⁽³⁾, Phe52⁽²⁾, Arg72⁽⁶⁾, Asp77⁽³⁾	Pro219 O–Cys73 N (2.9 Å)	1.08
Ser220	Gln70⁽²⁾, Pro71, Arg72⁽²⁾,	–	1.18
Tyr221	Pro71	Tyr221 N–Pro71 O (3.0 Å)	1.27
Phe289	Lys55, Asp61, Glu63⁽⁴⁾	–	15.52
Tyr290	Gly53⁽²⁾, Leu54⁽²⁾, Glu63⁽⁵⁾	Tyr290 OH–Glu63 OE1 (2.6 Å)	11.88
Pro291	Gly53, Leu54, Lys55⁽⁴⁾	–	8.87