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Seven snapshots in the time evolution of the contact matrix for β-lactoglobulin obtained respectively (a–g) at 6.4 × 10−8, 3.0 × 10−7, 7.9 × 10−7, 1.8 × 10−5, 5.2 × 10−4, 1.0 × 10–3 s, and essentially the contact matrix for the native structure. The arrows in c and e indicate regions that show local topological invariance but structural multiplicity; that is, the relevant torsion angles remain in the same R-basins but change geometries.
