Table 1.
Treatment group | |||||
Parameters | CQ | AQ | SP | AQ+SP | AQ+AS |
No. of patients | 42 | 39 | 40 | 83 | 83 |
No. females (%) | 20 (47.6%) | 22 (56.4%) | 26 (65.0%) | 42 (50.6%) | 38 (46.3%) |
Mean age (months. range) | 3.8 (0.6–14) | 3.3 (0.7–13) | 3.8 (0.5–12) | 3.9 (0.8–15) | 3.9 (0.5–15) |
Mean weight (kg. range) | 12.9 (7–35) | 13.0 (7.8–40) | 12.1 (6–34) | 14.3 (7–50) | 14.6 (6–54.5) |
Mean temperature (°C. range) | 38.4 (37.5–40.4) | 38.4 (37.5–40.8) | 38.5 (37.5–40.8) | 38.6 (37.5–41.0) | 38.6 (37.5–40.9) |
Geometric mean parasite density (/μl. range) | 21156 (1020–199058) | 25559 (1142–199800) | 25640 (1010–199531) | 22368 (1050–199048) | 22905 (1005–184881) |
Previous antimalrial therapy (%) | 2 (4.7%) | 1 (2.9%) | 2 (5.0%) | 2 (3.9%) | 3 (5.3%) |
Mean haemoglobin (g/dl. range) | 10.1 (6.2–14.0) | 10.0 (6.4–14.2) | 9.7 (6.2–12.4) | 10.2 (6.2–15.6) | 10.4 (6.2–15.5) |
CQ. Chloroquine; AQ. Amodiaquine; SP. Sulphadoxine-pyrimethamine; AS. artesunate.