Table 1.

LRA electrostatic contributions

System	ΔΔGelec(2Å)w→p	ΔΔGelec(4Å)w→p	ΔΔGelec(2Å→4Å)w→p
Ring1	−12.8	−13.3	−0.5
Ring2	−26.9	−32.0	−5.1
Ring3	5.0	1.9	−3.1

Energies are in kcal/mol. The calculated values were obtained by using Eq. 1 to evaluate the free energy of charging the indicated system. The Co-C bond distance (in Å) is given in brackets with the given charge state [e.g., Q(2Å) for 2-Å distance]. Ring₁, ring₂, and ring₃ represent, respectively, Co + corrin + Im, ribose, and adenine.