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. 2007 May 29;104(23):9691–9696. doi: 10.1073/pnas.0611379104

Fig. 1.

Fig. 1.

Adult hot-homozygous mutant phenotypes. Primary sexual phenotypes of hot homozygotes are indicated by F (female) and M (male) in parentheses with the sex chromosome composition. (A–D) Sex-dependent fin morphologies. (A) Wild-type XX female. (B) Wild-type XY male. Male fins have rougher edges and are larger than female fins. (C) Phenotypically female XY hot homozygote. (D) Phenotypically male XY hot homozygote. (E and F) External appearance of the hot-homozygous fish at 6 months. (Scale bar, 10 mm.) (E) XX hot homozygote, showing an expanded abdomen. (F) Phenotypically male XY hot mutant, with a less pronounced abdominal expansion. (G–J) Exposed gonads in wild-type and hot-homozygous fish. (G) Wild-type ovary. (H) Testis. (I) The abdominal cavity of a female hot homozygote occupied by a hypertrophic ovary. (J) Enlarged testis in a phenotypically male homozygote. (K) Comparisons of the gonads isolated from wild-type and hot homozygotes fish at 6 months; from left to right, XX hot ovary, XY hot testis, wild-type ovary and wild-type testis. (Scale bar, 10 mm.) (L) Changes in the gonad-somatic index (GSI = gonad weight/body weight in percentage) were plotted for wild-type and hot-homozygous mutant fish at 2, 3, 5, and 8 months after hatching. The averages measurements for at least four fish are indicated. Filled diamond, wild-type XX; open square, wild-type XY; filled circle, ovary-containing hot homozygotes of either XX or XY; open circle, XY hot homozygotes with testes.