Table II.
TCR Gene Usage and Predicted CDR3 Region Protein Sequences
| TCR-α T cell line | Gene usage | Vα | CDR3 | Jα | ||||
|---|---|---|---|---|---|---|---|---|
| CD8-1 | AV1S3, AJ17 | ...CAV | RRAAGNKLTF | GGG... | ||||
| CD8-2 | AV16S1, AJ34 | ...CAV | RHNTDKLIF | GTG... | ||||
| DN1 | AV8S2, AJ57 | ...CAE | PLSLPGGSEKLVF | GKG... | ||||
| DN.POTT | AV16S1, AJ31 | ...CAV | RDEGWARLMF | GDG... | ||||
| LDN5 | AV3S1, AJ9 | ...CAS | MYTGGFKTIF | GAG... | ||||
| TCR-β T cell line | Gene usage | Vβ | CDR3 | Jβ | ||||
| CD8-1 | BV2S1, BJ2S7 | ...CSA | RTYPGTGFYEQYF | GPG... | ||||
| CD8-2 | BV9S1, BJ2S1 | ...CAS | SSMYNEQFF | GPG... | ||||
| DN1 | BV5S1, BJ2S7 | ...CAS | SLVRRYEQYF | GPG... | ||||
| DN.POTT | BV6S1, BJ2S1 | ...CAS | SLTRSSHNEQFF | GPG... | ||||
| LDN5 | BV7S1, BJ2S1 | ...CAS | SQPIGGGEQFF | GPG... |
The TCR V and J gene usage for each T cell line is indicated. The predicted amino acid sequences from the CDR3 junctional regions of each TCR α and TCR β chain are shown with basic amino acid residues encoded by N nucleotides underscored. These sequence data are available from EMBL/GenBank/DDBJ under accession numbers AF107998–AF108007.